Fiber optic Raman spectroscopy offers labelfree identification of cancer in the bladder under in vivo conditions.However, state-of-the-art Raman Bun Pan Carriers technology does not enable to scan the entire bladder wall.Our multidimensional approach within the project Uro-MDD combines panoramic 3D-image reconstruction of white light cystoscopy and fluorescence lifetime imaging to define regions of interest for Raman-assisted diagnostics.First Raman results are presented from human control and cancer bladder specimens that demonstrated how to obtain specific molecular information.Such Raman images can be used in a clinical setting to determine cancer margins and the resection status.
Fiber probes are under development to translate the technique to in Clothing - Mens Bottoms vivo screening.